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Abstract Fast X-ray transients (FXTs) are a new observational class of phenomena with no clear physical origin. This is at least partially a consequence of limited multiwavelength follow-up of this class of transients in real time. Here we present deep optical (g- andi-band) photometry with Keck, and prompt radio observations with the Very Large Array of FXT 210423 obtained atδt≈ 14–36 days since the X-ray trigger. We use these multiband observations, combined with publicly available data sets, to constrain the presence and physical properties of on-axis and off-axis relativistic jets such as those that can be launched by neutron star mergers and tidal disruption events, which are among the proposed theoretical scenarios of FXTs. Considering a wide range of possible redshiftsz≤ 3.5, circumstellar medium densityn= 10⁻⁶–10⁻¹cm⁻³, and isotropic-equivalent jet kinetic energyE_k,iso= 10⁴⁸–10⁵⁵erg, we find that we can rule out wide jets with opening angleθ_j= 15° viewed within 10° off-axis. For more collimated jets (θ_j= 3°) we can only rule out on-axis (θ_obs= 0°) orientations. This study highlights the constraining power of prompt multiwavelength observations of FXTs discovered in real time by current (e.g., Einstein Probe) and future facilities. 

Abstract The High‐latitude Ionosphere Dynamics for Research Applications (HIDRA) model is part of the Multiscale Atmosphere‐Geospace Environment model under development by the Center for Geospace Storms NASA DRIVE Science Center. This study employs HIDRA to simulate upflows of H⁺, He⁺, O⁺, and N⁺ions, with a particular focus on the relative N⁺concentrations, production and loss mechanisms, and thermal upflow drivers as functions of season, solar activity, and magnetospheric convection. The simulation results demonstrate that N⁺densities typically exceed He⁺densities, N⁺densities are typically ∼10% O⁺densities, and N⁺concentrations at quiet‐time are approximately 50%–100% of N⁺concentrations during storm‐time. Furthermore, the N⁺and O⁺upflow fluxes show similar trends with variations in magnetospheric driving. The inclusion of ion‐neutral chemical reactions involving metastable atoms is shown to have significant effects on N⁺production rates. With this metastable chemistry included, the simulated ion density profiles compare favorably with satellite measurements from Atmosphere Explorer C and Orbiting Geophysical Observatory 6. 

Nucleation of clathrate hydrates at low temperatures is constrained by very long induction (wait) times, which can range from hours to days. Electronucleation (application of an electrical potential difference across the hydrate forming solution) can significantly reduce the induction time. This work studies the use of porous open-cell foams of various materials as electronucleation electrodes. Experiments with tetrahydrofuran (THF) hydrates reveal that aluminum and carbon foam electrodes can enable voltage-dependent nucleation, with induction times dependent on the ionization tendency of the foam material. Furthermore, we observe a non-trivial dependence of the electronucleation parameters such as induction time and the recalescence temperature on the water:THF molar ratio. This study further corroborates previously developed hypotheses which associated rapid hydrate nucleation with the formation of metal-ion coordination compounds. Overall, this work studies various aspects of electronucleation with aluminum and carbon foams. 

Nucleation of hydrates is constrained by very long induction (wait) times, which can range from hours to days. Electronucleation (application of an electrical potential across the precursor solution) can significantly reduce the induction time for nucleation. This study shows that porous aluminum foams (open-cell) enable near-instantaneous electronucleation at very low voltages. Experiments with tetrahydrofuran hydrates reveal that aluminum foam electrodes enable voltage-dependent nucleation with induction times of only tens of seconds at voltages as low as 20 V. Foam-based electrodes can reduce the induction time by up to 150X when compared to non-foam electrodes. Furthermore, this study reveals that electronucleation can be attributed to two distinct phenomena, namely bubble generation (due to electrolysis), and the formation of metal-ion coordination compounds. These mechanisms affect the induction time to different extents and depend on electrode material and polarity. Overall, this work uncovers the benefits of using foams for formation of hydrates, with foams aiding nucleation as well as propagation of the hydrate formation front. 

Abstract Aging, often considered a result of random cellular damage, can be accurately estimated using DNA methylation profiles, the foundation of pan-tissue epigenetic clocks. Here, we demonstrate the development of universal pan-mammalian clocks, using 11,754 methylation arrays from our Mammalian Methylation Consortium, which encompass 59 tissue types across 185 mammalian species. These predictive models estimate mammalian tissue age with high accuracy (r > 0.96). Age deviations correlate with human mortality risk, mouse somatotropic axis mutations and caloric restriction. We identified specific cytosines with methylation levels that change with age across numerous species. These sites, highly enriched in polycomb repressive complex 2-binding locations, are near genes implicated in mammalian development, cancer, obesity and longevity. Our findings offer new evidence suggesting that aging is evolutionarily conserved and intertwined with developmental processes across all mammals. 

Abstract The superτ-charm facility (STCF) is an electron–positron collider proposed by the Chinese particle physics community. It is designed to operate in a center-of-mass energy range from 2 to 7 GeV with a peak luminosity of 0.5 × 10³⁵cm⁻²·s⁻¹or higher. The STCF will produce a data sample about a factor of 100 larger than that of the presentτ-charm factory — the BEPCII, providing a unique platform for exploring the asymmetry of matter-antimatter (charge-parity violation), in-depth studies of the internal structure of hadrons and the nature of non-perturbative strong interactions, as well as searching for exotic hadrons and physics beyond the Standard Model. The STCF project in China is under development with an extensive R&D program. This document presents the physics opportunities at the STCF, describes conceptual designs of the STCF detector system, and discusses future plans for detector R&D and physics case studies. 

Abstract Long‐lasting Pc5 ultralow frequency (ULF) waves spanning the dayside and extending fromL ∼ 5.5into the polar cap region were observed by conjugate ground magnetometers. Observations from MMS satellites in the magnetosphere and magnetometers on the ground confirmed that the ULF waves on closed field lines were due to fundamental toroidal standing Alfvén waves. Monochromatic waves at lower latitudes tended to maximize their power away from noon in both the morning and afternoon sectors, while more broadband waves at higher latitudes tended to have a wave power maximum near noon. The wave power distribution and MMS satellite observations during the magnetopause crossing indicate surface waves on a Kelvin‐Helmholtz (KH) unstable magnetopause coupled with standing Alfvén waves. The more turbulent ion foreshock during an extended period of radial interplanetary magnetic field (IMF) likely plays an important role in providing seed perturbations for the growth of the KH waves. These results indicate that the Pc5 waves observed on closed field lines and on the open field lines of the polar cap were from the same source.